KNAW

Prof.dr. P.P. Tak Person

Prof.dr. P.P. Tak

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Completed research projects

(the most recent research is at the top)
Project leader The role of dendritic cel subsets in arthritis: an in vivo study
Researcher Determinants of drug resistance in synovial tissue of rheumatoid arthritis patients and implications for therapy
Project leader The role of CD44 splice-variants in reumatoïde arthritis
Project leader Clinical and molecular classification of very early rheumatoid arthritis
Project leader Role of cholinergic nervous system in collagen-induced arthritis in mice
Project leader Rheumatology
Project leader Diabetes mellitus and atherosclerosis
Project leader Functional properties of chemokines and chemokine receptors in inflammatory joint disease
Project leader Ras family GTPase regulation of fibroblast-like synoviocytes in rheumatoid arthritis
Project leader Comparative efficiency of AAV serotypes for gene transfer in arthritis
Project leader Feasibility of gene therapy in arthritis models using an artificial chromosome expression system
Project leader Developing salivary gland gene therapy for the local signs and symptoms of Sjögren’s syndrome
Project leader Consequences of CD97-CD55 interactions in arthritis
Project leader A double-blind study evaluating the effects of a C5a antagonist in comparison to placebo in patients with active rheumatoid arthritis
Project leader A double-blind, randomized, parallel group, placebo controlled, sequential dose escalation study of anti-MCP-1 therapy in patients with rheumatoid arthritis
Project leader A study to explore the changes in synovial inflammation and cytokine expression in patients with rheumatoid arthritis after treatment with prednisolone
Project leader Cost-effectiveness clinical study on infliximab treatment in rheumatoid arthritis
Project leader Mechanistic study on the effects of infliximab therapy in rheumatoid arthritis
Project leader Mechanistic study on the effects of infliximab therapy in psoriatic arthritis
Project leader Effect of IKK-2 dominant negative mutant gene transfer in adjuvant arthritis in rats with adeno associated viral vectors

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