Person

Prof.dr. T.K. Sixma

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Completed research projects

(the most recent research is at the top)
Project leader	Exploring new uses of AChBP as model for ligand-gated ion channel research
Project leader	L1 and Alu elements: structural and functional analysis of human non-LTR retrotransposons
Project leader	Subtle gene modification to study the role of the mismatch repair complex MSH2/MSH6 in mutation avoidance and tumor suppression
Project leader	Purchase of X-ray diffraction equipment (X-ray mirrors, image plate, nitrogen cryo-stream)
Supervisor	Structural and functional analysis of the human L1/Alu retroposition machinery
Project leader	Structural analysis of the mechanism of ubiquitin conjugation, a generalized cellular addressing system, that controls protein and DNA stability
Project leader	Structure/function analysis of MutS homologs in hereditary non-polyposis colon cancer (HNPCC)
Project leader	Structure-function studies of cyclin D1 in complex with nuclear hormone receptors and/or coactivators.