| Titel |
Fatigue in multiple sclerosis. Reciprocal relationships with physical disabilities and depression |
| Gepubliceerd in |
Journal of Psychosomatic Research, Vol. 53, p.775-781. ISSN 0022-3999. |
| Auteur |
Schreurs, K.M.G.; Ridder, D.T.D. de; Bensing, J. |
| Datum |
2002 |
| Trefwoord(en) |
Depression, Fatigue, Multiple sclerosis, Physical disabilities |
| Taal |
Engels |
| Type |
artikel |
| Uitgever |
Elsevier |
| Samenvatting |
Objective: To explore relations of fatigue, physical disabilities, and depression in patients with multiple sclerosis (MS)
cross-sectionally and over time. Methods: Ninety-eight MS patients were interviewed twice at an interval of a year.
Relationships of physical and mental fatigue, and reduced activity and motivation with depression and physical disabilities were established cross-sectionally by regression analyses and longitudinally
by structural equation modelling. Results: Crosssectionally, physical fatigue was related with physical disabilities,
and mental fatigue was associated with depression. Prospectively, physical fatigue was a predictor of the physical disabilities of a year later. The reverse relationship of physical disabilities predicting the physical fatigue of one year later was, however, not significant, while depression predicted this physical fatigue and reduced activity of a year later. Depression did not predict the later mental fatigue nor was depression predicted by preceding
fatigue experiences. Conclusions: Fatigue in MS should be studied over time as relationships of fatigue with physical and
mental health change during the course of a year. Moreover, differentiating in fatigue experiences sheds light on the relationship
of fatigue with physical and mental health. |
| Publicatie |
http://igitur-archive.library.uu.nl/fss/2007-0705-203706/UUi... |
| Persistent Identifier |
URN:NBN:NL:UI:10-1874-21908 |
| Metadata |
XML |
| Repository |
Universiteit Utrecht |