Metabolomics technologies and metabolite identification (2007)

Title Metabolomics technologies and metabolite identification
Published in TrAC : Trends in Analytical Chemistry, Vol. 26, No. 9, p.855-866. ISSN 0165-9936.
Author Moco, S.I.A.; Bino, R.J.; Vos, de C.H.; Vervoort, J.J.M.
Date 2007
Reference(s) Laboratorium voor Plantenfysiologie, Biochemie, PRI Bioscience, PRI Directie, Laboratory of Plant Physiology, Biochemistry, PRI Bioscience, PRI Management
Language English
Type Article
Abstract Metabolomics studies rely on the analysis of the multitude of small molecules (metabolites) present in a biological system. Most commonly, metabolomics is heavily supported by mass spectrometry (MS) and nuclear magnetic resonance (NMR) as parallel technologies that provide an overview of the metabolome and high-power compound elucidation. Over and above large-scale analysis, a major effort is needed for unequivocal identification of metabolites. The combination of liquid chromatography (LC)-MS and NMR is a powerful methodology for identifying metabolites. Better chemical characterization of the metabolome will undoubtedly enlarge knowledge of any biological system.
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Persistent Identifier urn:nbn:nl:ui:32-358543
Metadata XML
Repository Wageningen University & Research Centre

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