| Title | Enzymatic method for inactivation of aminoglycosides during measurement of postantibiotic effect |
|---|---|
| Published in | Antimicrobial Agents and Chemotherapy. ISSN 0066-4804. |
| Author | Hollander, den J.G. (Jan); Mouton, J.W. (Johan); Bakker-Woudenberg, I.A.J.M. (Irma); Vleggaar, F.P. (Frank); Goor, van M.P.J.; Verbrugh, H.A. (Henri) |
| Date | 1996-01-01 |
| Language | English |
| Type | article |
| Abstract | To determine the postantibiotic effect of aminoglycosides, two methods are currently being used to remove the test drug: repeated washing and dilution. An enzymatic inactivation method of removing gentamicin and tobramycin was developed and compared with the dilution method. This enzymatic method provides a rapid and simple alternative method of removing aminoglycosides which results in reliable postantibiotic-effect values. |
| Publication | http://hdl.handle.net/1765/8625 |
| Persistent Identifier | urn:NBN:nl:ui:15-1765/8625 |
| Metadata | XML |
| Repository | Erasmus University Rotterdam |
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