Facioscapulohumerale spierdystrofie (2010)

Title Facioscapulohumerale spierdystrofie
Published in Nederlands Tijdschrift voor Tandheelkunde, Vol. 117, p.11-14. ISSN 0028-2200.
Author Wilbers, J.; Frants, R.R.; Engelen, B.G.M. van; Padberg, G.W.A.M.; Maarel, S.M. van der
Date 2010
Type Article
Abstract Facioscapulohumeral muscular dystrophy is clinically mainly characterized by progressive weakness of the facial, shoulder and upper arm muscles. It is an autosomal dominant heriditary disease, caused by a contraction of a repetitive DNA element at the end of the long arm of chromosome 4. This contraction causes the local relaxation of the chromatin structure and likely dysregulation of one or more genes. Oral health care providers can play a significant role in the early recognition, as the often asymmetric facial weakness is frequently the first symptom. Adequate oral health care is needed because of the facial weakness.
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Persistent Identifier urn:nbn:nl:ui:22-2066/87385
Metadata XML
Repository Radboud University Nijmegen

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