| Title | Reduced context effects on retrieval in first-episode schizophrenia |
|---|---|
| Published in | PLoS One, Vol. 5, No. 4, p.e10356-. ISSN 19326203. |
| Author | L.M. Talamini; L. de Haan; D.H. Nieman; D.H. Linszen; M. Meeter |
| Date | 2010 |
| Type | article |
| Abstract | Background: A recent modeling study by the authors predicted that contextual information is poorly integrated into episodic representations in schizophrenia, and that this is a main cause of the retrieval deficits seen in schizophrenia. Methodology/Principal Findings: We have tested this prediction in patients with first-episode schizophrenia and matched controls. The benefit from contextual cues in retrieval was strongly reduced in patients. On the other hand, retrieval based on item cues was spared. Conclusions/Significance: These results suggest that reduced integration of context information into episodic representations is a core deficit in schizophrenia and one of the main causes of episodic memory impairment. |
| Publication | http://dare.uva.nl/record/374338 |
| Persistent Identifier | urn:nbn:nl:ui:29-374338 |
| Metadata | XML |
| Repository | University of Amsterdam |
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