| Titel | Encouraging survival rates in patients with acute myocardial infarction treated with an intra-aortic balloon pump |
|---|---|
| Gepubliceerd in | Netherlands Heart Journal, Vol. 19, No. 3, p.112-118. ISSN 1568-5888. |
| Auteur | Valk, S.D.A. (Suzanne); Cheng, J.M. (Jin Ming); Uil, den C.A. (Corstiaan); Lagrand, W.K. (Wim); Ent, van der M. (Martin); Sande, van de M. (Meike); Domburg, van R.T. (Ron); Simoons, M.L. (Maarten) |
| Datum | 2011-03-01 |
| Trefwoord(en) | Outcome, Survival, Acute myocardial infarction, Predictors, Intra-aortic balloon pump |
| Taal | Engels |
| Type | artikel |
| Samenvatting | Objective To evaluate a 30-day and long-term outcome of patients with acute myocardial infarction (AMI) treated with intra-aortic balloon pump (IABP) counterpulsation and to identify predictors of a 30-day and long-term all-cause mortality. Methods Retrospective cohort study of 437 consecutive AMI patients treated with IABP between January 1990 and June 2004. A Cox proportional hazards model was used to identify predictors of a 30-day and long-term all-cause mortality. Results Mean age of the study population was 61±11 years, 80% of the patients were male, and 68% had cardiogenic shock. Survival until IABP removal after successful haemodynamic stabilisation was 78% (n=341). Cumulative 30-day survival was 68%. Median follow-up was 2.9 years (range, 6 months to 15 years). In patients who survived until IABP removal, cumulative 1-, 5-, and 10-year survival was 75%, 61%, and 39%, respectively. Independent predictors of higher long-term mortality were prior cerebrovascular accident (hazard ratio (HR), 1.8; 95% confidence interval (CI), 1.0-3.4), need for antiarrhythmic drugs (HR, 2.3; 95% CI, 1.5-3.3), and need for renal replacement therapy (HR, 2.3; 95% CI, 1.2-4.3). Independent predictors of lower long-term mortality were primary percutaneous coronary intervention (PCI; HR, 0.6; 95% CI, 0.4-1.0), failed thrombolysis with rescue PCI (HR, 0.5; 95% CI, 0.3-0.9), and coronary artery bypass grafting (HR, 0.3; 95% CI, 0.1-0.5). Conclusions Despite high in-hospital mortality in patients with AMI treated with IABP, a favourable number of patients survived in the long-term. These results underscore the value of aggressive haemodynamic support of patients throughout the acute phase of AMI. |
| Publicatie | http://hdl.handle.net/1765/25539 |
| Persistent Identifier | urn:NBN:nl:ui:15-1765/25539 |
| Metadata | XML |
| Repository | Erasmus Universiteit Rotterdam |
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