This is the protocol for a review and there is no abstract. The objectives are as follows:
1. To assess the short and long-term efficacy of different medication classes (benzodiazepines, selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), other medications) for different anxiety disorders in older adults aged 55 years or over compared with placebo.
2. To assess the relative efficacy of different medication classes for anxiety disorders in older adults aged 55 years and over.
3. To assess adverse events associated with the use of each medication class, as well as comparing differences in the incidence of adverse events between different medication classes.
4. To conduct a narrative review to additionally describe trials omitted from the quantitative analysis due to missing data.