| Titel |
Enzymatic method for inactivation of aminoglycosides during measurement of postantibiotic effect |
| Gepubliceerd in |
Antimicrobial Agents and Chemotherapy. ISSN 0066-4804. |
| Auteur |
Hollander, den J.G. (Jan); Mouton, J.W. (Johan); Bakker-Woudenberg, I.A.J.M. (Irma); Vleggaar, F.P. (Frank); Goor, van M.P.J.; Verbrugh, H.A. (Henri) |
| Datum |
1996-01-01 |
| Trefwoord(en) |
Comparative Study, Acetyltransferases/*pharmacology, Bacteria/drug effects/*metabolism, Gentamicins/metabolism, Microbial Sensitivity Tests/*methods, Tobramycin/metabolism, Anti-Bacterial Agents/*metabolism |
| Taal |
Engels |
| Type |
artikel |
| Samenvatting |
To determine the postantibiotic effect of aminoglycosides, two methods are
currently being used to remove the test drug: repeated washing and
dilution. An enzymatic inactivation method of removing gentamicin and
tobramycin was developed and compared with the dilution method. This
enzymatic method provides a rapid and simple alternative method of
removing aminoglycosides which results in reliable postantibiotic-effect
values. |
| Publicatie |
http://hdl.handle.net/1765/8625 |
| Persistent Identifier |
urn:NBN:nl:ui:15-1765/8625 |
| Metadata |
XML |
| Repository |
Erasmus Universiteit Rotterdam |