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Enzymatic method for inactivation of aminoglycosides during... (1996) Open access

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Titel Enzymatic method for inactivation of aminoglycosides during measurement of postantibiotic effect
Gepubliceerd in Antimicrobial Agents and Chemotherapy. ISSN 0066-4804.
Auteur Hollander, den J.G. (Jan); Mouton, J.W. (Johan); Bakker-Woudenberg, I.A.J.M. (Irma); Vleggaar, F.P. (Frank); Goor, van M.P.J.; Verbrugh, H.A. (Henri)
Datum 1996-01-01
Trefwoord(en) Comparative Study, Acetyltransferases/*pharmacology, Bacteria/drug effects/*metabolism, Gentamicins/metabolism, Microbial Sensitivity Tests/*methods, Tobramycin/metabolism, Anti-Bacterial Agents/*metabolism
Taal Engels
Type artikel
Samenvatting To determine the postantibiotic effect of aminoglycosides, two methods are currently being used to remove the test drug: repeated washing and dilution. An enzymatic inactivation method of removing gentamicin and tobramycin was developed and compared with the dilution method. This enzymatic method provides a rapid and simple alternative method of removing aminoglycosides which results in reliable postantibiotic-effect values.
Publicatie http://hdl.handle.net/1765/8625
Persistent Identifier urn:NBN:nl:ui:15-1765/8625
Metadata XML
Repository Erasmus Universiteit Rotterdam
Erasmus Universiteit Rotterdam

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