| This program concerns various methods of renal replacement therapy: haemodialysis, peritoneal dialysis and transplantation. In the clinical setting we try to find optimal treatment modalities for acute renal failure i.e. continuous dialysis techniques (CAVHD, CVVH) and for haemodynamic instability during intermittent dialysis. Activation patterns of peritoneal macrophages derived from CAPD patients during peritonitis are also studied. The main topic of the program is immunological monitoring of kidney and heart transplant recipients. We study the cascades of immunological factors that lead to acute and chronic rejection, attempt to find strategies to prevent and treat these processes and aim at development of tolerance long after organ transplantation. |
