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Premalignant lesion & chronic inflammatory bowel disease

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Title Premalignant lesion & chronic inflammatory bowel disease
Period 01 / 1988 - unknown
Status Completed
Research number OND1281223
Data Supplier METIS Erasmus Universiteit Rotterdam

Abstract

Concerning premalignant lesion in the distal oesophagus the investigation aims on the one hand at the determination of prognostic parameters in Barrett epithelium, that can predict if malignity will arise; on the other hand at the treatment of Barrett epithelium by photodynamic methods. Regarding the colon carcinoma research is done on effective screening and intervention stategies. Mediators of inflammation in Crohn's disease and colitis ulcerosa are investigated concerning their mutual interaction, and effects by drugs are evaluated. Clinical research is done into the effects of somatostatine and IL-10.

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Related people

Project leader Prof.dr. P.D. Siersema
Project leader Prof. J.H.P. Wilson
Project leader Dr. F.J. Zijlstra

Classification

A70000 Public health and health care
D21800 Immunology, serology
D23120 Oncology
D23220 Internal medicine
D23340 Biopharmacology, toxicology

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