| Our research program focusses on the treatment and prevention of viral disorders. A main component of the program is the search to optimize the treatment of HIV-1 infection, with on one hand an effort to increase the potency of antiretroviral therapies, on the other hand an effort to understand and minimize toxicities of drugs utilized. These issues are being addressed in both clinical trials - on a local and on a global scale - and a national cohort study (ATHENA project). Another research line is prevention of mother-to-child transmission of HIV-1. This research is largely targetted at Africa, in settings where breastfeeding is the norm. The identification of effective, affordable and sustainable antiretroviral therapies for resource poor settings has become a research priority. Additional research lines are the treatment of hepatitis B and hepatitis C virus infections, in both HIV-1 co-infected and in non-co-infected patients, and Varicella zoster virus vaccination. |
