| The cognitive capacities of a sleeping brain are still unknown. Investigators suggest a function of sleep in information processing and more specifically in the strengthening of memory (Cipolli, 1995; Plihal and Born, 1999), but a discussion about the differential cognitive functions of slow wave sleep (SWS) and rapid eye movement (REM) sleep is still going on. Every day we acquire new information and form new memories in our brain. The specific role of sleep in memory processes is investigated by Stickgold In his research showed Stickgold (1999) that associative memory is altered during sleep. Contrary to the normal pattern of priming, awakened from REM showed a greater priming effect by weak primes than by strong primes. Stickgold suggest that the connectivity to old memories is being changed in the neural network of associative memory and new learned information (the weak associated concept) will have more attention during remsleep. The results of his research suggest that cognition during remsleep is qualitatively different from that of waking and Non-rem. According to Stickgold et al (1999) associative priming can be used to obtain evidence for the view that sleep is involved in memory processing. The goal of this study is a replication of Stickgolds research to uncover the function of sleep in the strengthening of newly formed associations. A second project addresses the processing of information reaching a person during sleep. The fact that a sleeping person can be aroused by a powerful stimulus, and sometimes even by a low intensity, but relevant, stimulus, shows that the brain is able to process and evaluate incoming information to a certain extent. This project aims at developing a method to assess the amount of information that reaches the sleeping brain and what a sleeping brain still can do with this information. The experiment will proceed along the line of sensory gating . The concept of sensory gating implies that a certain amount of information is transferred to higher levels of the brain, depending on the level of alertness or consciousness. The neurophysiological transfer ratio concept, developed by Coenen et al, (1972) gives an idea of how far this gate is open or closed during sleep and wakefulness. The aim of this study is to study information processing during sleep; during light and deep sleep, as well as during active REM-sleep. This sensory gating concept that is rooted in neuronal research will be tested in a behavioral-neuropsychological way. |