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Wie heeft de leiding mbt de cognitieve controle? Neurale interacties bij...

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Titel Wie heeft de leiding mbt de cognitieve controle? Neurale interacties bij adaptieve besluitvorming
Looptijd 03 / 2005 - 07 / 2010
Status Afgesloten
Onderzoeknummer OND1307820
Leverancier gegevens Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO)

Samenvatting (EN)

If circumstances call for immediate performance adjustments, howdo neural interactions decide when to recruit cognitive control? Howis adaptive decision making (deciding which action to take in theface of rapidly changing demands) established without invoking ahomunculus? Medial frontal cortex (MFC) is involved in performance monitoring:evaluating outcome vis-¿-vis expectancy, and detecting performanceerrors or conflicting response tendencies. MFC is not involved inimplementing appropriate adjustments itself; this is the corebusiness of prefrontal cortex (PFC), in particular lateral PFC andorbitofrontal cortex (OFC). There is some initial evidence for adirect contingency between performance monitoring and adaptivebehavior. The specific mechanism by which detection of conflict ornegative outcome in MFC engages the recruitment of control, however,remains undisclosed. How do PFC processes involved in implementingcontrol become engaged when activations in MFC signal the need toinstigate performance adjustments? Who is in command of recruitingcognitive control? This question, crucial to understanding adaptive cognitive controlbut thus far resistant to (if not exempt of) experimental scrutiny,is the main issue to be tackled in the intended research: what arethe neurocognitive mechanisms that underlie the connections betweensignaling the need to increase the level of control (in MFC, indexedin EEG/fMRI measures), and the subsequent recruitment of control (inPFC, indexed in fMRI and behavioral adjustments, especially alteredreaction-time distributions). Paradigmatic innovations and newcombinations of methods will help scrutinize this missing link. Further explorations involve individual differences in these adaptivedecision-making mechanisms related to old age. We will investigatethe extent to which set shifting, goal-directed action selection, andperformance monitoring involve differential patterns of activationamong young and older adults. Correlations between age-differentialbrain activation patterns and specific aspects of behavioral decline

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Classificatie

A84400 Cognitieve ontwikkeling, perceptie
D51000 Psychologie

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