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VLAG3-C1 Toxicology

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Titel VLAG3-C1 Toxicology
Looptijd 01 / 2005 - onbekend
Status Lopend
Onderzoeknummer OND1310101

Betrokken organisaties

Penvoerder Voeding, Levensmiddelentechnologie, Agrobiotechnologie en Gezondheid - VLAG (WUR)

Betrokken personen

Projectleider Prof.dr.ir. M.H. Zwietering

Bovenliggende onderzoeksactiviteit(en)

Deelprogramma VLAG3-C Core programme C. Food safety

Onderliggende lopende onderzoeksactiviteiten

PBK and PBD models to characterize dose-dependent effects indetoxification and DNA binding of α,β-unsaturated aldehydes.
PBK and PBD models to characterize dose-dependent effects indetoxification and DNA binding of a,Ã?-unsaturated aldehydes.
New PBBK- and PBTD-modelling based concepts fo low-dose cancer riskextrapolation for alkenylbenzenes aiming at better risk assessment ofthese carcinogenic natural food ingredients.
The influence of phase II conjugation and deconjugation in thebiological activity of cocoa flavonoids.
Impact water matrix on effect and side effect of UV/H2O2 treatment.
Flavonoids as bioactive ingredients against cardiovascular diseases: a risk-benefit evaluation.
Toxicogenomics-based in vitro alternatives of thyroid hormone disruption tests.
Healthy ageing: Development of new therapeutic strategies and functional (food) ingredients for treatment and prevention of diabetestype 2.
The role of ERα and ER� in the risk benefit analysis of mixturesof estrogens; Effect of differential ER expression on cell proliferation and apoptosis.
Development of in vitro reporter gene bioassays for detection of beneficial health effects of functional foods.
Matrix mediated modulation of the toxicity of alkylalkoxy benzenes.
Toxicogenomics-based in vitro alternatives for the uterotrophicassay.
Cacao: Post-harvest technology. A contribution to the improvement of processed beans quality in the Island of Sao Tome
Risk assessment of Listeria monocytogenes in cooked meat products

Classificatie

A71000 Voeding
D22700 Toxicologie (milieu)

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