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Drug Eluting Stent Implantation for High Risk Patients and Novel...

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Titel Drug Eluting Stent Implantation for High Risk Patients and Novel Technologies in Percutaneous Coronary Intervention
Looptijd 07 / 2005 - 02 / 2010
Status Afgesloten
Dissertatie Ja
Onderzoeknummer OND1310898
Leverancier gegevens Website COEUR

Samenvatting (EN)

Recent studies show that the local application of antiproliferative drugs for prevention of restenosis via a stent delivery system inhibits or reduces restenosis successfully. In the era of drug-eluting stents (DES), percutaneous coronary intervention has become a therapeutic option of choice. Especially, sirolimus and paclitaxel are used as safe, antiproliferative drugs. However, in-stent restenosis still remains a problem. Other dark sides of DES include: early and late stent thrombosis; increasing neo-intima with time; incomplete stent apposition; and stent fracture. As DES consist of a drug, a polymer, and a stent platform, several drugs with durable or erodable polymers and some kinds of platform have been tested. In his PhD project, Shuzou Tanimoto investigates the efficacy of new technologies and devices. In addition, he analyzes the long-term outcome and safety of new DES.

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A31400 Medische hulpmiddelen
A34800 Geneesmiddelen en bestrijdingsmiddelen
A70000 Volksgezondheid en gezondheidszorg
D23220 Inwendige geneeskunde
D24200 Preventieve gezondheidszorg, GVO

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