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Discovery of novel circadian clock components in light signaling pathways

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Title Discovery of novel circadian clock components in light signaling pathways
Period 02 / 2005 - unknown
Status Completed
Research number OND1313347
Data Supplier Website BCN

Abstract

The circadian clock regulates processes from gene expression to behaviour, such that activity is characteristic according to time of day. Neurospora crassa is considered a simple genetic model system for investigations into clock mechanisms and components. In Neurospora, clock components are part of light input pathways (WHITE COLLAR-1 is both a clock component and a blue light photoreceptor). Furthermore, there is evidence for more complex light signaling mechanisms and the Neurospora genome sequence indicates additional photoreceptor candidates. Novel light regulated processes will be identified, and their regulation by novel Neurospora photoreceptors will be determined. The relationship of these processes to clock regulation will be assessed to find novel clock components and mechanisms.

Related organisations

Related people

Supervisor Prof.dr. S. Daan
Researcher Drs. S. Ghosh

Classification

A70000 Public health and health care
D21200 Biophysics, clinical physics
D21400 Genetics

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