| With the proportional increase of the aging populations more and more people suffer from neurological disorders. For better treatment of these patients an early diagnosis is of great importance. Electroencephalography (EEG) is an important diagnostic tool in clinical neurophysiology. However, a disadvantage of these techniques is its low spatial resolution as compared to imaging techniques like MRI, CT and PET. On the other hand, the temporal resolution of EEG is much higher and the costs are much lower. With the development of multi-channel (with 64, 128 or 256 electrodes) EEG extra data is recorded and the spatial resolution of EEG has improved. This led to new or improved applications of EEG. So far multi-channel EEG, event related potential (ERP) and evoked potential (EP) recordings have been mostly used to gain further insight into brain physiology in healthy subjects or in group studies of psychiatric diseases. Only a limited number of studies report clinical applications. In this project we are interested in the clinical value of multi-channel EPs and ERPs. We will develop new analysis techniques for multi-channel EPs and ERPs to enhance diagnosis and prognosis for individual patients suffering from neurological disorders. We will focus on somatosensory evoked potentials (SEP), P300 ERPs and visual evoked potentials (VEP). |
