| Intestinal epithelial cells of the intestines undergo apoptosis (a form of programmed cell death) as a regular part of their life cycle. Apoptosis of senescing cells leads to a rejuvenation of the intestinal wall and leads to improved functioning of the intestines. Some lactic acid bacteria may induce an acceleration of this process, such that a suboptimal intestinal functioning can be improved. The interaction of bacteria and epithelium will be visualised as well as possible using bioinformatics, transcriptomics and proteomics. |
