Ethnic differences in hypertension, diabetes, dyslipidemia and the role of contextual factors: A comparative analysis between the Netherlands (the SUNSET study), and the UK studies (the Newcastle Heart Study and Health Survey for England)
07 / 2007 - onbekend
Hart- en vaatziekten komen vaker voor onder etnische minderheden. Er is weinig bekend over de redenen daarvoor. Deze studie combineert gegevens uit grote onderzoeken in Nederland en het Verenigd Koninkrijk. Er wordt onderzocht of omgevingsfactoren in deze landen de etnische verschillen kunnen verklaren.
Cardiovascular disease (CVD) is a major public health burden and the rates are higher in some minority populations than in White populations. The causes of the excess risks are incompletely understood and pose a high level scientific challenge. International comparisons provide a good opportunity to gain more insight into the role of contextual factors (i.e. lifestyle, health care and socio-economic factors) in ethnic disparities in health. Aim: To combine large health studies from the Netherlands (the SUNSET study), and the UK (Newcastle Heart Study and Health Survey for England (HSE)) to examine the role of contextual factors on differences in biomedical cardiovascular risk factors between populations with similar ethnic backgrounds living in the Netherlands (Hindustani-Surinamese, African-Surinamese and White-Dutch) and the UK (South-Asian, African-Caribbean, Black-African and White-British) using standardised data. The advantage of comparing the two countries is the greater variation within the groups in contextual factors as we study whether variation in CVD risk factors vary with these contexts.Data and methods: Each investigator will provide individual patient data on biomedical cardiovascular risk factors i.e. blood pressure, hypertension, fasting glucose, impaired fasting glucose (IFG), diabetes, total-cholesterol, HDL-cholesterol, LDL-cholesterol and triglyceride; lifestyle (smoking, alcohol consumption, physical activity, body mass index and waist circumference), health care (i.e. early detection, treatment and control of hypertension, diabetes and dyslipidemia) and socio-demographics. The three datasets will be standardised and merged in the Amsterdam Academic Medical Centre (AMC).Expected results: The study will establish ethnic differences in cardiovascular risk factors and will provide important information on the role of contextual factors in ethnic disparities in health. Such information is indispensable for devising effective measures in primary prevention, improve services, and inevitably, raise standards of care and prevention for all populations in both countries.