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Optimal experimental designs for functional magnetic resonance imaging

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Title Optimal experimental designs for functional magnetic resonance imaging
Period 10 / 2006 - 04 / 2011
Status Completed
Dissertation Yes
Research number OND1320985
Data Supplier Website IOPS

Abstract

Cognitive processes can be studied with functional magnetic resonance imaging (fMRI) experiments. Different within subject and between subject designs exist with their own advantages and disadvantages. This research project aims at finding optimal designs for fMRI experiments that have maximal efficiency and maximal power for finding real effects. By means of results from the statistical theory of optimal designs for generalized linear mixed effects models, including both random and fixed parameters together with (auto)correlated errors, the problem of finding optimal designs can be formulated as a nonlinear optimisation problem. The optimal designs will be empirically evaluated with real fMRI data.

Related organisations

Related people

Supervisor Prof.dr. M.P.F. Berger
Supervisor Prof.dr. R.W. Goebel
Co-supervisor Prof.dr. G.J.P. van Breukelen
Doctoral/PhD student Dr. B. Maus

Classification

D51000 Psychology
D61000 Sociology

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