The research program Clinical Epidemiology focuses on the application of clinical epidemiologic methods towards clinical research, with special attention for use of innovative methods and innovation of these methods. Research topics include the full spectrum of clinical epidemiology, i.e. aetiology, diagnosis, prognosis and treatment, and include the performance of meta-analysis within these research areas. There is a focus on patient-important outcome and the potential for incorporation into guidelines and implementation in medical practice. The medical context is based on the specific interest fields of tenured staff, and in addition guided by interest for participation of clinicians.