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The Transcription Factor Network in Embryonic Stem Cells

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Title The Transcription Factor Network in Embryonic Stem Cells
Period 07 / 2007 - 10 / 2010
Status Completed
Dissertation Yes
Research number OND1325578
Data Supplier Website EMC

Abstract

Stem cells maintain their unique characteristics using specific transcription factors and chromatin factors. We study how these factors fulfill their function by using biochemical purification from embryonic stem cells and/or neural stem cells. Examples of studied factors are ISWI chromatin remodeling complexes and the Oct4 transcription factor

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Supervisor Prof.dr. F.G. Grosveld
Researcher Dr. U. Akinci
Project leader Dr. R.A. Poot
Doctoral/PhD student Dr. D.L.C. van den Berg

Classification

D21300 Biochemistry
D21500 Histology, cell biology

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