|Title||Effectiveness of two intensive counselling methods for smoking cessation and relapse prevention in persons with coronary heart disease|
|Period||11 / 2008 - 03 / 2013|
|Data Supplier||ZonMw Projectenbank|
|This research proposal ultimately aims to provide hospitalized smoking coronary heart disease patients with proven (cost)effective smoking cessation strategies. For this purpose we will test two counselling interventions: face-to-face counselling (FC) and telephone counselling (TC). If subgroups show to profit more of one intervention, they should receive most (cost) effective one.We have planned three studies, a first on effectiveness of the interventions on smoking cessation and health outcomes, a second on cost effectiveness and a third on feasibility and dissemination, with following goals.STUDY 1 aims to assess:- effects of TC and FC on smoking cessation and health outcomes 6 and 12 months after baseline. This will be tested in an experiment with patients receiving TC or FC or usual care. In general, we expect comparable point prevalence abstinence rates in FC and TC, 60% and 55% at 6 and 12 months. We also expect differential effects in subgroups. Low SES groups will profit more from FC compared to higher SES groups and groups with a high quitting motivation will profit more from TC than those with low motivation. For this reason, we also expect that TC is more cost effective in smokers motivated to quit and FC more cost effective in low SES patients. Next to these expected moderation effects, possible moderation of gender, diagnosis and disease severity will be explored. In the usual care condition, cessation rates of 43% and 35% are expected after 6 and 12 months (see Strategies for rationale). For health outcomes we expect in both experimental groups fewer hospital readmissions, cardiac events, mortality and greater improvements in cholesterol ratio and blood pressure. Figures are not defined because corrections for baseline scores, medication, age, gender are needed. - appreciation/ experiences of patients with TC and FC and changes in cognitive determinants through which smoking cessation is expected to occur.STUDY 2 aims at assessing cost effectiveness and budgetary impact of TC, FC and usual care. Study 1 and 2 will be conducted together in the same sample. Study 2 compares health outcomes and smoking cessation outcomes (see study 1) with costs of the interventions, including usual care.STUDY 3 aims to assess experiences of counsellors, nurses, cardiologists with TC and FC, in order to map feasibility and relevant conditions needed for large-scale dissemination of the interventions (in-depth interviews and two surveys).
Cardiovascular disease is the leading cause of death, and coronary heart diseases have an important share in this . Smoking cessation after development of coronary heart disease improves prognosis more than any other treatment and prevents future cardiovascular diseases. Yet, 57% of those who smoked prior to a cardiac event persist in smoking or relapse . Usual smoking cessation care in Dutch cardiology wards -by ward nurses- is not intensive enough  and nurses experience difficulties in providing this care. Hence, we need improved intensive and feasible smoking cessation interventions for Dutch cardiac inpatients. Previous studies and reviews [5-10] provide strong indications that intensive counselling interventions including relapse prevention strategies and pharmacotherapy are effective. They are expected to be feasible in practice if carried out by smoking cessation professionals instead of ward nurses and can be provided by telephone of face-to-face. However, such interventions have not yet been tested in cardiac inpatients nor cost-effectiveness is clear.This research proposal aims to provide hospitalized coronary heart disease patients who smoke with proven (cost)effective smoking cessation interventions. However, subgroups may profit more from a different type of intervention and should receive most (cost)effective one. Therefore, two interventions will be compared to each other and to usual care. The interventions mainly consist of intensive counselling by smoking cessation professionals, either by telephone in one intervention and by face-to-face counselling in the other. These comparable interventions differ in delivery mode and duration. Reviews concluded both to be equally effective in general populations [8,9,11] and the Dutch foundation on smoking and health (STIVORO) currently offers them to Dutch public. In our proposal, the interventions start in hospital and continue after discharge. In both interventions, ward nurses start assessing patients smoking behaviour followed by providing stop-smoking advice and referral to smoking cessation counselling. In one intervention, we deliver counselling by telephone (TC), in the other face-to-face (FC). Both interventions include nicotine replacement therapy. We study both TC and FC because we have strong indications that persons with high quit motivation profit more from telephone counselling than those with low quit motivation . We expect low SES groups often less motivated to quit-  to profit more from face-to-face counselling than high SES groups . Telephone counselling is expected to be more cost effective in patients with high quit motivation, face-to-face counselling in low SES patients. We propose following studies:STUDY 1: - To assess (differential) effects of TC and FC on smoking cessation and health outcomes in cardiac inpatients.- To assess patients appreciation of and experiences with the interventions.Study 1 is an experiment in cardiac wards. We will test effects of TC and FC on smoking cessation against each other and a control group receiving usual care. Based on previous studies (see Power calculations in Strategy ) we in general expect similar effectiveness. We estimate point prevalence abstinence in the experimental groups at 60% at 6 months, against 43% in the control group. After 12 months, we expect 55% abstinence in experimental groups and 35% in the control group. We also expect previously mentioned differential effects in subgroups. Smoking status will be verified by saliva sample on cotinine and intention to treat analyses will be applied. In both experimental groups, we also expect fewer hospital readmissions, cardiac events, mortality and greater improvements in TC/HDL cholesterol ratio and blood pressure.STUDY 2: - To assess incremental cost-effectiveness and budgetary impact of the interventions comparing them to each other and to usual care.Study 2 is an economic evaluation study that will be conducted in the sample of study 1 by comparing the improved outcomes in patients (see study 1) with incremental costs of the interventions and usual care. Resource use will be registered, as well as smoking, cardiac related health care use and productivity losses. Costs per quitter from healthcare and societal perspectives are computed. Modelling will be used to extrapolate outcomes to a lifetime horizon to also assess incremental costs per QALY gained. The budgetary impacts of each intervention will be estimated from insurer and hospital perspectives.STUDY 3: - To assess feasibility of the interventions, experiences of counsellors, nurses and cardiologists in working with them, and detecting relevant conditions for large-scale dissemination.Study 3 is a dissemination study consisting of three sub studies, namely qualitative in-depth interviews followed by two quantitative surveys.The project will result in a dissertation and two interventions ready for large-scale dissemination.
|Nederlandse Vereniging voor Hart en Vaat Verpleegkundigen|
|Stichting Volksgezondheid en Roken|
|Project leader||Dr. C.A.W. Bolman|
|D24200||Health education, prevention|
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