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Biomedical genomics : Genome structure and function in health and disease

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Titel Biomedical genomics : Genome structure and function in health and disease
Looptijd 01 / 2009 - onbekend
Status Lopend
URL http://www.hubrecht.eu/research/delaat/research.html
Onderzoeknummer OND1339338
Leverancier gegevens Website Hubrecht Institute

Samenvatting (EN)

Aim of our research is to understand the relationship between genome structure and function in mammalian cells. Techniques We use and develop novel genomics approaches (next generation sequencing and microarrays) and bioinformatic analysis tools, in combination with high-resolution microscopy techniques and molecular and cell biology strategies. We recently developed 4C technology, a novel high-throughput genomics approach that uniquely allows screening the entire genome for DNA regions that interact with a DNA segment of choice. 4C is expected to importantly contribute to our understanding of nuclear architecture.

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Projectleider Prof.dr. W.L. de Laat

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