| Agression and anti-social behavior in children can be treated in some cases by training the parents in specific parenting skills. Parent Management Training Oregon (PMTO) is an evidence-based treatment program that is helpful for about 50% of the aggressive children. The study focuses on the relation of anti-social behavior and aggression with neurobiological and neuropsychological factors. The question is addressed whether these factors can help predict effectiveness of treatment. Main focus is on selfregulation and empathy. |