Intravascular imaging and interventional cardiology
01 / 2010 - onbekend
The decision making process for patients with obstructive coronary artery disease requiring revascularization is evolving. Historically, patients with the most complex coronary artery disease were preferentially treated by surgical revascularization: however technological advances in percutaneous therapy have ensured that many of these patients can now receive equally effective treatment with percutaneous coronary intervention (PCI). Intertwined with these developments are a lower threshold to investigate patients with symptoms suggestive of coronary artery disease, an increasingly elderly population in need of revascularization, the changing dynamics of the doctor-patient relationship, and a greater emphasis on guideline driven patient care. Consequently decisions regarding revascularization are now more complex than ever before. The advent of drug eluting stents (DES), which consist of a drug (immunosuppressive or antiproliferative drug), a polymer and a metallic platform, has revolutionized the practice of interventional cardiology by significantly reducing the rates of restenosis and repeat revascularization as compared to bare metal stents. Within this project, this subject is studied in detail while taking into account evolvement in stent development, as well as secular trends in acute and chronic benefits of percutanuous coronary interventions.