The creation of new firms represents an important source of growth and job creation in the economy . However, it is also well known that a large proportion of new firms die within few years after creation. The proposed research explores the determinants of the performance of new firms, focusing on the strategies followed by these organizations as they seek to innovate and commercialize their ideas. The research will be based on the analysis of new and existing data sets, collected from Statistics Netherlands and EIM Business & Policy Research. The research covers three thematic areas. The first theme relates to the impact of the external environment on new firms, and focuses on the role of technology in shaping the opportunities faced by these organizations. The second theme explores the processes within new firms and examines differences in managerial practices in the way new firms protect and commercially exploit new ideas. The third theme integrates the external environment with the internal practices of new firms by exploring the interplay between the external environment, managerial choices of new firms, and their subsequent performance. The research will demonstrate the effectiveness of different entrepreneurial strategies in the context of specific environmental conditions.